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MLB Prop Bets: Philadelphia Phillies vs St. Louis Cardinals (August 21, 2026)

The St. Louis Cardinals (66-63) face the Philadelphia Phillies (70-58) at Citizens Bank Park on Friday at 6:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Hunter Dobbins is the probable pitcher for the Cardinals, while Jesus Luzardo is the probable pitcher for the Phillies.

  • The Cardinals have a 53-71-5 O/U record this season (meaning 53 games have gone over the total runs line, 71 have gone under and five have resulted in a push). The Phillies have a 57-63-8 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.4 runs per game this season (18th in the league). Comparatively, the Phillies are averaging 4.5 (T15th).
  • In the field, the Cardinals are allowing 4.4 runs per game this season (T13th in the league), while the Phillies are allowing an average of 4.4 runs (15th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .241 (ranking 21st in the Major leagues), while the Phillies are batting .241 (20th).

Home Runs

  • In terms of total home runs this season, the Phillies have hit 155 (T9th in the Major Leagues). Meanwhile, the Cardinals have managed 133 (T21st).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 557 RBIs to rank 10th in the MLB this season. Comparatively, the Phillies have recorded 555 RBIs to rank 11th.

Pitching Insights:

Earned Run Average

  • The Phillies have an earned run average of 4.12 this season (16th in the Majors), while The Cardinals have an ERA of 4.04 (12th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 1000 this season, ranking 24th in the MLB. Meanwhile, the Phillies rank 1st for total strikeouts, recording 1259.

Opponent Batting Average

  • Opponents are batting an average of .250 against the Phillies this season (22nd in the Major Leagues). Comparatively, the Cardinals' opponents are at .250 (23rd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 29-21-79 12-10-44 17-11-35 12-8-22 17-13-57 0-0-0 4-1-5
    Phillies 35-28-65 23-13-29 11-15-36 29-20-47 6-8-18 1-0-0 2-1-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 55-36-38 29-17-20 26-19-18 22-10-10 33-26-28 0-0-0 4-1-5
    Phillies 57-45-26 33-20-12 23-25-14 47-32-17 10-13-9 1-0-0 6-2-2

NRFI/YRFI

  • The NRFI is 70-59 in Cardinals games this season. The Phillies have a 62-66 NRFI record.

Last Time They Met

The Cardinals recorded an upset 7-1 victory over the Phillies at Busch Stadium when these teams last met on August 12. Alec Burleson went yard en route to that victory, hitting a home run to go with 3 RBIs.