MLB Prop Bets: St. Louis Cardinals vs Baltimore Orioles (August 25, 2026)
The Baltimore Orioles (63-68) face the St. Louis Cardinals (66-66) at Busch Stadium on Tuesday at 7:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Chris Bassitt is the probable pitcher for the Orioles, while Matthew Liberatore is the probable pitcher for the Cardinals. The Cardinals are favored to win at -124, while the Orioles are at +116. The total runs line is set at 8.0, with OVER at -118 and UNDER at -102.
- The Orioles (-193) have a 68-63 Run Line record this season, while the Cardinals (+158) hold a record of 71-61.
- The Orioles have a 64-62-5 O/U record this season (meaning 64 games have gone over the total runs line, 62 have gone under and five have resulted in a push). The Cardinals have a 56-71-5 O/U record.
Scoring Insights
- The Orioles are averaging 4.5 runs per game this season (17th in the league). Comparatively, the Cardinals are averaging 4.4 (18th).
- In the field, the Orioles are allowing 4.7 runs per game this season (22nd in the league), while the Cardinals are allowing an average of 4.4 runs (16th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Orioles are at .235 (ranking 27th in the Major leagues), while the Cardinals are batting .241 (21st).
Home Runs
- In terms of total home runs this season, the Cardinals have hit 137 (21st in the Major Leagues). Meanwhile, the Orioles have managed 159 (T10th).
Runs Batted In
- Finally, looking at their runs batted in, the Orioles have recorded 563 RBIs to rank 15th in the MLB this season. Comparatively, the Cardinals have recorded 570 RBIs to rank T11th.
Pitching Insights:
Earned Run Average
- The Cardinals have an earned run average of 4.14 this season (17th in the Majors), while The Orioles have an ERA of 4.19 (19th).
Strikeouts
- Turning our attention to total strikeouts, the Orioles have recorded 1038 this season, ranking 23rd in the MLB. Meanwhile, the Cardinals rank 25th for total strikeouts, recording 1015.
Opponent Batting Average
- Opponents are batting an average of .252 against the Cardinals this season (23rd in the Major Leagues). Comparatively, the Orioles' opponents are at .254 (26th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Orioles | 25-26-80 | 10-10-48 | 15-16-32 | 10-8-42 | 15-18-38 | 0-0-0 | 2-0-8 |
| Cardinals | 31-22-79 | 12-10-44 | 19-12-35 | 12-8-22 | 19-14-57 | 0-0-0 | 6-2-2 |
Lead After Three Innings
The Orioles are +110 to lead after three innings, while the Cardinals are -140.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Orioles | 42-53-36 | 24-26-18 | 18-27-18 | 19-21-20 | 23-32-16 | 0-0-0 | 0-4-6 |
| Cardinals | 56-38-38 | 29-17-20 | 27-21-18 | 22-10-10 | 34-28-28 | 0-0-0 | 4-3-3 |
NRFI/YRFI
The NRFI market is paying -125 and the YRFI is paying -105.
- The NRFI is 73-58 in Orioles games this season. The Cardinals have a 70-62 NRFI record.
Last Time They Met
The Cardinals recorded a 6-4 victory over the Orioles at Oriole Park at Camden Yards when these teams last met on May 28, 2025. Brendan Donovan dominated at the plate in that matchup, notching 1 home run, 2 singles and 2 RBIs.
