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MLB Prop Bets: Los Angeles Angels vs Seattle Mariners (September 16, 2026)

The Seattle Mariners (70-82) face the Los Angeles Angels (58-93) at Angel Stadium of Anaheim on Wednesday at 9:38pm (ET). Let's take a look at the MLB Prop Bets for the matchup. George Kirby is the probable pitcher for the Mariners, while Yusei Kikuchi is the probable pitcher for the Angels. The Mariners are favored to win at -136, while the Angels are at +113. The total runs line is set at 8.0, with OVER at -114 and UNDER at -105.

  • The Mariners (+123) have a 58-94 Run Line record this season, while the Angels (-149) hold a record of 76-75.
  • The Mariners have a 79-64-9 O/U record this season (meaning 79 games have gone over the total runs line, 64 have gone under and nine have resulted in a push). The Angels have a 62-86-3 O/U record.

Scoring Insights

  • The Mariners are averaging 4.1 runs per game this season (28th in the league). Comparatively, the Angels are averaging 4.1 (29th).
  • In the field, the Mariners are allowing 4.5 runs per game this season (17th in the league), while the Angels are allowing an average of 4.5 runs (18th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Mariners are at .232 (ranking 29th in the Major leagues), while the Angels are batting .234 (28th).

Home Runs

  • In terms of total home runs this season, the Angels have hit 146 (T28th in the Major Leagues). Meanwhile, the Mariners have managed 175 (T13th).

Runs Batted In

  • Finally, looking at their runs batted in, the Mariners have recorded 595 RBIs to rank 28th in the MLB this season. Comparatively, the Angels have recorded 585 RBIs to rank 29th.

Pitching Insights:

Earned Run Average

  • The Angels have an earned run average of 4.19 this season (19th in the Majors), while The Mariners have an ERA of 4.22 (20th).

Strikeouts

  • Turning our attention to total strikeouts, the Mariners have recorded 1290 this season, ranking 12th in the MLB. Meanwhile, the Angels rank 8th for total strikeouts, recording 1349.

Opponent Batting Average

  • Opponents are batting an average of .236 against the Angels this season (8th in the Major Leagues). Comparatively, the Mariners' opponents are at .250 (22nd).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Mariners 35-41-76 21-17-37 14-24-39 28-28-58 7-13-18 0-0-0 1-4-5
    Angels 41-29-81 27-11-38 14-18-43 9-2-16 32-27-65 0-0-0 2-1-7

Lead After Three Innings

The Mariners are -130 to lead after three innings, while the Angels are +100.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Mariners 59-58-35 32-25-18 27-33-17 42-41-31 17-17-4 0-0-0 1-5-4
    Angels 57-57-37 34-20-22 23-37-15 15-8-4 42-49-33 0-0-0 4-3-3

NRFI/YRFI

The NRFI market is paying -135 and the YRFI is paying +105.

  • The NRFI is 69-83 in Mariners games this season. The Angels have a 76-75 NRFI record.

Last Time They Met

The Angels recorded a 2-1 victory over the Mariners at Angel Stadium of Anaheim yesterday. Josh Lowe was unstoppable in that matchup, hitting a home run, a single and recording an RBI. The Angels have now won four straight at Angel Stadium of Anaheim against the Mariners.