MLB Prop Bets: Boston Red Sox vs Minnesota Twins (May 22, 2026)
The Minnesota Twins (23-27) face the Boston Red Sox (22-27) at Fenway Park on Friday at 7:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Connor Prielipp is the probable pitcher for the Twins, while Payton Tolle is the probable pitcher for the Red Sox. The Red Sox are favored to win at -156, while the Twins are at +129. The total runs line is set at 7.5, with OVER at -113 and UNDER at -106.
- The Twins (-168) have a 26-24 Run Line record this season, while the Red Sox (+139) hold a record of 21-28.
- The Twins have a 27-19-4 O/U record this season (meaning 27 games have gone over the total runs line, 19 have gone under and four have resulted in a push). The Red Sox have a 21-27-1 O/U record.
Scoring Insights
- The Twins are averaging 4.6 runs per game this season (9th in the league). Comparatively, the Red Sox are averaging only 3.7 (29th).
- In the field, the Twins are allowing 4.6 runs per game this season (21st in the league), while the Red Sox are allowing an average of 3.9 runs (7th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Twins are at .236 (ranking 18th in the Major leagues), while the Red Sox are batting .240 (15th).
Home Runs
- In terms of total home runs this season, the Red Sox have hit 36 (29th in the Major Leagues). Meanwhile, the Twins have managed 55 (13th).
Runs Batted In
- Finally, looking at their runs batted in, the Twins have recorded 217 RBIs to rank 11th in the MLB this season. Comparatively, the Red Sox have recorded 173 RBIs to rank 29th.
Pitching Insights:
Earned Run Average
- The Red Sox have an earned run average of 3.68 this season (9th in the Majors), while The Twins have an ERA of 4.20 (18th).
Strikeouts
- Turning our attention to total strikeouts, the Twins have recorded 382 this season, ranking 26th in the MLB. Meanwhile, the Red Sox rank 21st for total strikeouts, recording 401.
Opponent Batting Average
- Opponents are batting an average of .234 against the Red Sox this season (12th in the Major Leagues). Comparatively, the Twins' opponents are at .242 (17th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Twins | 11-11-28 | 9-4-16 | 2-7-12 | 2-3-6 | 9-8-22 | 0-0-0 | 1-3-6 |
| Red Sox | 4-17-28 | 1-5-16 | 3-12-12 | 1-8-21 | 3-9-7 | 0-0-0 | 0-6-4 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Twins | 22-16-12 | 14-7-8 | 8-9-4 | 6-3-2 | 16-13-10 | 0-0-0 | 4-3-3 |
| Red Sox | 15-19-15 | 8-7-7 | 7-12-8 | 9-9-12 | 6-10-3 | 0-0-0 | 2-5-3 |
NRFI/YRFI
The NRFI market is paying -135 and the YRFI is paying +100.
- The NRFI is 28-22 in Twins games this season. The Red Sox have a 26-23 NRFI record.
Last Time They Met
The Red Sox recorded a 9-5 victory over the Twins at Target Field when these teams last met on April 15. Trevor Story was unstoppable in that matchup, hitting a home run, a double and recording 5 RBIs.
