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MLB Prop Bets: Cleveland Guardians vs San Diego Padres (August 16, 2026)

The San Diego Padres (66-58) face the Cleveland Guardians (60-64) at Progressive Field on Sunday at 1:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Casey Mize is the probable pitcher for the Padres, while Tanner Bibee is the probable pitcher for the Guardians. The Padres are favored to win at -114, while the Guardians are at -105. The total runs line is set at 8.5, with OVER at -105 and UNDER at -115.

  • The Padres (+144) have a 63-61 Run Line record this season, while the Guardians (-175) hold a record of 56-68.
  • The Padres have a 56-66-2 O/U record this season (meaning 56 games have gone over the total runs line, 66 have gone under and two have resulted in a push). The Guardians have a 60-64-0 O/U record.

Scoring Insights

  • The Padres are averaging 4.3 runs per game this season (21st in the league). Comparatively, the Guardians are averaging 4.0 (28th).
  • In the field, the Padres are allowing 4.3 runs per game this season (11th in the league), while the Guardians are allowing an average of 4.2 runs (9th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .237 (ranking 23rd in the Major leagues), while the Guardians are batting .233 (27th).

Home Runs

  • In terms of total home runs this season, the Guardians have hit 119 (28th in the Major Leagues). Meanwhile, the Padres have managed 136 (T19th).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 511 RBIs to rank 21st in the MLB this season. Comparatively, the Guardians have recorded 471 RBIs to rank 28th.

Pitching Insights:

Earned Run Average

  • The Guardians have an earned run average of 3.84 this season (8th in the Majors), while The Padres have an ERA of 4.11 (17th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 1009 this season, ranking 20th in the MLB. Meanwhile, the Guardians rank 4th for total strikeouts, recording 1150.

Opponent Batting Average

  • Opponents are batting an average of .238 against the Guardians this season (9th in the Major Leagues). Comparatively, the Padres' opponents are at .245 (18th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 21-23-80 12-12-39 9-11-39 13-9-33 8-14-47 0-0-2 2-0-8
    Guardians 27-19-78 16-9-36 11-10-42 18-11-45 9-8-33 0-0-0 3-0-7

Lead After Three Innings

The Padres are -105 to lead after three innings, while the Guardians are -125.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 40-53-31 23-26-14 16-26-17 16-22-17 24-31-14 1-1-0 3-7-0
    Guardians 44-39-41 27-18-16 17-21-25 29-24-21 15-15-20 0-0-0 3-5-2

NRFI/YRFI

The NRFI market is paying -130 and the YRFI is paying +100.

  • The NRFI is 76-48 in Padres games this season. The Guardians have a 72-52 NRFI record.

Last Time They Met

The Guardians recorded a 6-1 victory over the Padres at Progressive Field yesterday. Steven Kwan went yard en route to that victory, hitting a home run to go with an RBI. That result snapped the Padres' six-game winning streak against the Guardians.