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MLB Prop Bets: Chicago Cubs vs St. Louis Cardinals (August 16, 2026)

The St. Louis Cardinals (62-61) face the Chicago Cubs (72-52) at Wrigley Field on Sunday at 3:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Hunter Dobbins is the probable pitcher for the Cardinals, while Edward Cabrera is the probable pitcher for the Cubs. The Cubs are favored to win at -162, while the Cardinals are at +134. The total runs line is set at 9.0, with OVER at +100 and UNDER at -120.

  • The Cardinals (-156) have a 67-56 Run Line record this season, while the Cubs (+129) hold a record of 62-62.
  • The Cardinals have a 49-69-5 O/U record this season (meaning 49 games have gone over the total runs line, 69 have gone under and five have resulted in a push). The Cubs have a 65-56-3 O/U record.

Scoring Insights

  • The Cardinals are averaging 4.4 runs per game this season (19th in the league). Comparatively, the Cubs are averaging +0.8 more at 5.2 runs (2nd).
  • In the field, the Cardinals are allowing 4.4 runs per game this season (14th in the league), while the Cubs are allowing an average of 4.3 runs (12th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Cardinals are at .239 (ranking 21st in the Major leagues), while the Cubs are batting .249 (8th).

Home Runs

  • In terms of total home runs this season, the Cubs have hit 157 (8th in the Major Leagues). Meanwhile, the Cardinals have managed 127 (22nd).

Runs Batted In

  • Finally, looking at their runs batted in, the Cardinals have recorded 524 RBIs to rank 16th in the MLB this season. Comparatively, the Cubs have recorded 603 RBIs to rank 2nd.

Pitching Insights:

Earned Run Average

  • The Cubs have an earned run average of 4.10 this season (16th in the Majors), while The Cardinals have an ERA of 4.04 (12th).

Strikeouts

  • Turning our attention to total strikeouts, the Cardinals have recorded 935 this season, ranking 26th in the MLB. Meanwhile, the Cubs rank 25th for total strikeouts, recording 947.

Opponent Batting Average

  • Opponents are batting an average of .244 against the Cubs this season (16th in the Major Leagues). Comparatively, the Cardinals' opponents are at .252 (24th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 26-20-77 12-10-44 14-10-33 10-7-21 16-13-56 0-0-0 2-0-8
    Cubs 27-25-72 17-13-31 10-12-41 24-14-47 3-11-25 0-0-0 1-5-4

Lead After Three Innings

The Cardinals are +114 to lead after three innings, while the Cubs are -145.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Cardinals 52-35-36 29-17-20 23-18-16 20-9-9 32-26-27 0-0-0 3-3-4
    Cubs 46-41-37 29-18-14 17-23-23 39-24-22 7-17-15 0-0-0 3-4-3

NRFI/YRFI

The NRFI market is paying -105 and the YRFI is paying -125.

  • The NRFI is 68-55 in Cardinals games this season. The Cubs have a 69-55 NRFI record.

Last Time They Met

The Cardinals recorded an upset 8-4 victory over the Cubs at Wrigley Field yesterday. Joshua Baez was crushing the ball in that matchup, hitting 3 home runs and recording 5 RBIs.