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MLB Prop Bets: Houston Astros vs Arizona Diamondbacks (September 5, 2026)

The Arizona Diamondbacks (74-68) face the Houston Astros (73-69) at Daikin Park on Saturday at 7:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Brandon Pfaadt is the probable pitcher for the Diamondbacks, while Ethan Pecko is the probable pitcher for the Astros. The Astros are favored to win at -112, while the Diamondbacks are at -108. The total runs line is set at 8.5, with OVER at -110 and UNDER at -110.

  • The Diamondbacks (+153) have a 79-63 Run Line record this season, while the Astros (-186) hold a record of 73-69.
  • The Diamondbacks have a 59-74-9 O/U record this season (meaning 59 games have gone over the total runs line, 74 have gone under and nine have resulted in a push). The Astros have a 71-62-9 O/U record.

Scoring Insights

  • The Diamondbacks are averaging 4.4 runs per game this season (17th in the league). Comparatively, the Astros are averaging 4.5 (11th).
  • In the field, the Diamondbacks are allowing 4.5 runs per game this season (17th in the league), while the Astros are allowing an average of 4.8 runs (24th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Diamondbacks are at .242 (ranking 19th in the Major leagues), while the Astros are batting .240 (20th).

Home Runs

  • In terms of total home runs this season, the Astros are one of the best in the Major Leagues, hitting 186 to rank 5th. Alternatively, the Diamondbacks are at the opposite end of the home run standings, hitting just 139 (26th).

Runs Batted In

  • Finally, looking at their runs batted in, the Diamondbacks have recorded 600 RBIs to rank 16th in the MLB this season. Comparatively, the Astros have recorded 611 RBIs to rank 13th.

Pitching Insights:

Earned Run Average

  • The Astros have an earned run average of 4.53 this season (24th in the Majors), while The Diamondbacks have an ERA of 4.15 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Diamondbacks have recorded 969 this season, ranking 29th in the MLB. Meanwhile, the Astros rank 9th for total strikeouts, recording 1248.

Opponent Batting Average

  • Opponents are batting an average of .238 against the Astros this season (12th in the Major Leagues). Comparatively, the Diamondbacks' opponents are at .249 (21st).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Diamondbacks 30-39-73 18-15-37 12-24-34 17-13-28 13-26-45 0-0-2 0-3-7
    Astros 38-36-68 22-14-37 16-22-31 17-14-32 21-22-36 0-0-0 1-2-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Diamondbacks 43-67-32 27-25-18 15-41-14 25-18-15 18-49-17 1-1-0 1-4-5
    Astros 50-57-35 31-26-16 19-31-19 24-26-13 26-31-22 0-0-0 4-1-5

NRFI/YRFI

  • The NRFI is 64-78 in Diamondbacks games this season. The Astros also have a 64-78 NRFI record.

Last Time They Met

The Astros recorded a 3-1 victory over the Diamondbacks at Daikin Park yesterday. Despite being on the wrong side of that result, Gabriel Moreno did what he could, hitting a home run. The Astros have now won four straight against the Diamondbacks.