MLB Prop Bets: San Francisco Giants vs San Diego Padres (September 12, 2026)
The San Diego Padres (79-68) face the San Francisco Giants (62-86) at Oracle Park on Saturday at 4:05pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Michael King is the probable pitcher for the Padres, while Cesar Perdomo is the probable pitcher for the Giants. The Padres are favored to win at -160, while the Giants are at +132. The total runs line is set at 8.0, with OVER at -110 and UNDER at -110.
- The Padres (+109) have a 76-71 Run Line record this season, while the Giants (-131) hold a record of 75-73.
- The Padres have a 64-78-5 O/U record this season (meaning 64 games have gone over the total runs line, 78 have gone under and five have resulted in a push). The Giants have a 69-66-13 O/U record.
Scoring Insights
- The Padres are averaging 4.3 runs per game this season (23rd in the league). Comparatively, the Giants are averaging 4.2 (24th).
- In the field, the Padres are allowing 4.1 runs per game this season (T7th in the league), while the Giants are allowing an average of 4.7 runs (23rd).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Padres are at .238 (ranking 21st in the Major leagues), while the Giants are batting .247 (10th).
Home Runs
- In terms of total home runs this season, the Giants have hit 167 (16th in the Major Leagues). Meanwhile, the Padres have managed 161 (20th).
Runs Batted In
- Finally, looking at their runs batted in, the Padres have recorded 603 RBIs to rank 21st in the MLB this season. Comparatively, the Giants have recorded 601 RBIs to rank 24th.
Pitching Insights:
Earned Run Average
- The Giants have an earned run average of 4.37 this season (23rd in the Majors), while The Padres have an ERA of 3.89 (9th).
Strikeouts
- Turning our attention to total strikeouts, the Padres have recorded 1200 this season, ranking 18th in the MLB. Meanwhile, the Giants rank 27th for total strikeouts, recording 1107.
Opponent Batting Average
- Opponents are batting an average of .248 against the Giants this season (20th in the Major Leagues). Comparatively, the Padres' opponents are at .239 (13th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Padres | 26-27-94 | 15-13-47 | 11-14-45 | 18-11-44 | 8-16-50 | 0-0-2 | 3-1-6 |
| Giants | 38-35-75 | 22-9-42 | 16-26-33 | 11-6-29 | 27-29-46 | 0-0-0 | 6-3-1 |
Lead After Three Innings
The Padres are -154 to lead after three innings, while the Giants are +120.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Padres | 49-60-38 | 29-29-17 | 19-30-21 | 25-26-22 | 24-34-16 | 1-1-0 | 4-3-3 |
| Giants | 50-60-38 | 25-26-22 | 25-34-16 | 16-15-15 | 34-45-23 | 0-0-0 | 4-5-1 |
NRFI/YRFI
The NRFI market is paying -120 and the YRFI is paying -110.
- The NRFI is 89-58 in Padres games this season. The Giants have a 72-76 NRFI record.
Last Time They Met
The Padres recorded a 7-5 victory over the Giants at Oracle Park yesterday. Despite being on the wrong side of that result, Rafael Devers went yard in that matchup, hitting a home run to go with 4 RBIs. The Padres have now won four straight against the Giants.
