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MLB Prop Bets: Kansas City Royals vs Chicago White Sox (September 22, 2026)

The Chicago White Sox (80-76) face the Kansas City Royals (67-89) at Kauffman Stadium on Tuesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Anthony Kay is the probable pitcher for the White Sox, while Daniel Lynch is the probable pitcher for the Royals.

  • The White Sox have an 88-66-2 O/U record this season (meaning 88 games have gone over the total runs line, 66 have gone under and two have resulted in a push). The Royals have a 68-82-6 O/U record.

Scoring Insights

  • The White Sox are averaging 4.7 runs per game this season (6th in the league). Comparatively, the Royals are averaging only 4.2 (T23rd).
  • In the field, the White Sox are allowing 4.4 runs per game this season (15th in the league), while the Royals are allowing an average of 4.9 runs (25th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the White Sox are at .234 (ranking 26th in the Major leagues), while the Royals are batting .245 (13th).

Home Runs

  • In terms of total home runs this season, the Royals have hit 162 (22nd in the Major Leagues). Meanwhile, the White Sox have managed 199 (6th).

Runs Batted In

  • Finally, looking at their runs batted in, the White Sox have been outstanding this season, recording 698 RBIs to rank 6th in the MLB. Comparatively, the Royals have performed poorly in this area, recording only 624 RBIs to rank 25th.

Pitching Insights:

Earned Run Average

  • The Royals have an earned run average of 4.66 this season (27th in the Majors), while The White Sox have an ERA of 4.11 (13th).

Strikeouts

  • Turning our attention to total strikeouts, the White Sox have recorded 1286 this season, ranking 17th in the MLB. Meanwhile, the Royals rank 28th for total strikeouts, recording 1130.

Opponent Batting Average

  • Opponents are batting an average of .259 against the Royals this season (28th in the Major Leagues). Comparatively, the White Sox's opponents are at .242 (16th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    White Sox 39-40-77 22-18-38 17-22-39 12-6-29 27-34-48 0-0-0 3-1-6
    Royals 36-37-83 19-19-37 17-18-46 10-14-29 26-23-54 0-0-0 3-1-6

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    White Sox 56-55-45 31-23-24 25-32-21 18-9-20 38-46-25 0-0-0 5-4-1
    Royals 50-69-37 29-30-16 21-39-21 15-25-13 35-44-24 0-0-0 4-4-2

NRFI/YRFI

  • The NRFI is 71-85 in White Sox games this season. The Royals have a 77-79 NRFI record.

Last Time They Met

The Royals recorded a 5-4 victory over the White Sox at Rate Field when these teams last met on June 28. Miguel Vargas was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs. That result snapped the White Sox's six-game winning streak against the Royals.