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MLB Prop Bets: St. Louis Cardinals vs Milwaukee Brewers (May 4, 2026)

The Milwaukee Brewers (18-15) face the St. Louis Cardinals (20-14) at Busch Stadium on Monday at 7:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Brandon Sproat is the probable pitcher for the Brewers, while Kyle Leahy is the probable pitcher for the Cardinals. The Brewers are favored to win at -115, while the Cardinals are at -105. The total runs line is set at 8.0, with OVER at -112 and UNDER at -108.

  • The Brewers (+144) have a 19-14 Run Line record this season, while the Cardinals (-175) hold a record of 22-12.
  • The Brewers have a 17-16-0 O/U record this season (meaning 17 games have gone over the total runs line and 16 have gone under). The Cardinals have an 18-16-0 O/U record.

Scoring Insights

  • The Brewers are averaging 5.2 runs per game this season (4th in the league). Comparatively, the Cardinals are averaging 4.9 (9th).
  • In the field, the Brewers are allowing only 3.8 runs per game this season (5th in the league), while the Cardinals are allowing an average of 4.9 runs (23rd).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Brewers are at .239 (ranking 17th in the Major leagues), while the Cardinals are batting .241 (15th).

Home Runs

  • In terms of total home runs this season, the Cardinals are one of the best in the Major Leagues, hitting 44 to rank T4th. Alternatively, the Brewers are at the opposite end of the home run standings, hitting just 22 (29th).

Runs Batted In

  • Finally, looking at their runs batted in, the Brewers have recorded 165 RBIs to rank 8th in the MLB this season. Comparatively, the Cardinals have recorded 162 RBIs to rank 9th.

Pitching Insights:

Earned Run Average

  • The Cardinals have an earned run average of 4.54 this season (24th in the Majors), while The Brewers have an ERA of 3.56 (4th).

Strikeouts

  • Turning our attention to total strikeouts, the Brewers have recorded 309 this season, ranking 7th in the MLB. Meanwhile, the Cardinals rank 30th for total strikeouts, recording 236.

Opponent Batting Average

  • Opponents are batting an average of .261 against the Cardinals this season (26th in the Major Leagues). Comparatively, the Brewers' opponents are at .231 (8th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Brewers 8-8-17 4-5-9 4-3-8 7-5-10 1-3-7 0-0-0 4-1-5
    Cardinals 6-5-23 2-2-14 4-3-9 0-2-1 6-3-22 0-0-0 2-1-7

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Brewers 13-11-9 7-6-5 6-5-4 10-5-7 3-6-2 0-0-0 5-2-3
    Cardinals 15-10-9 8-4-6 7-6-3 1-1-1 14-9-8 0-0-0 7-3-0

NRFI/YRFI

The NRFI market is paying -130 and the YRFI is paying +100.

  • The NRFI is 17-16 in Brewers games this season. The Cardinals have an 18-16 NRFI record.

Last Time They Met

The Cardinals recorded a 5-1 victory over the Brewers at Busch Stadium when these teams last met on September 21, 2025. Ivan Herrera went yard en route to that victory, hitting a home run to go with 2 RBIs.