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MLB Prop Bets: Arizona Diamondbacks vs Pittsburgh Pirates (May 6, 2026)

The Pittsburgh Pirates (19-17) face the Arizona Diamondbacks (17-17) at Chase Field on Wednesday at 9:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Paul Skenes is the probable pitcher for the Pirates, while Michael Soroka is the probable pitcher for the Diamondbacks. The Pirates are favored to win at -156, while the Diamondbacks are at +129. The total runs line is set at 8.0, with OVER at -105 and UNDER at -115.

  • The Pirates (+113) have a 19-17 Run Line record this season, while the Diamondbacks (-136) hold a record of 21-13.
  • The Pirates have a 19-16-1 O/U record this season (meaning 19 games have gone over the total runs line, 16 have gone under and one has resulted in a push). The Diamondbacks have an 18-12-4 O/U record.

Scoring Insights

  • The Pirates are averaging 5.0 runs per game this season (7th in the league). Comparatively, the Diamondbacks are averaging 4.7 (11th).
  • In the field, the Pirates are allowing 4.4 runs per game this season (15th in the league), while the Diamondbacks are allowing an average of 5.3 runs (27th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Pirates are at .248 (ranking 10th in the Major leagues), while the Diamondbacks are batting .248 (11th).

Home Runs

  • In terms of total home runs this season, the Diamondbacks have hit 34 (T21st in the Major Leagues). Meanwhile, the Pirates have managed 38 (T14th).

Runs Batted In

  • Finally, looking at their runs batted in, the Pirates have recorded 174 RBIs to rank 5th in the MLB this season. Comparatively, the Diamondbacks have recorded 153 RBIs to rank 14th.

Pitching Insights:

Earned Run Average

  • The Diamondbacks have an earned run average of 4.92 this season (29th in the Majors), while The Pirates have an ERA of 3.85 (9th).

Strikeouts

  • Turning our attention to total strikeouts, the Pirates have recorded an impressive 334 this season, ranking T2nd in the MLB. Contrastingly, the Diamondbacks rank 29th for total strikeouts, recording only 251.

Opponent Batting Average

  • Opponents are batting an average of .255 against the Diamondbacks this season (23rd in the Major Leagues). Comparatively, the Pirates' opponents are at .223 (5th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Pirates 12-5-19 7-3-10 5-2-9 8-3-9 4-2-10 0-0-0 3-2-5
    Diamondbacks 8-10-16 4-4-6 4-6-8 3-2-4 5-8-12 0-0-2 2-3-5

Lead After Three Innings

The Pirates are -154 to lead after three innings, while the Diamondbacks are +120.

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Pirates 16-9-11 10-4-6 6-5-5 11-5-4 5-4-7 0-0-0 3-4-3
    Diamondbacks 10-17-7 5-4-5 4-12-2 5-1-3 5-16-4 1-1-0 2-7-1

NRFI/YRFI

The NRFI market is paying -140 and the YRFI is paying +105.

  • The NRFI is 19-17 in Pirates games this season. The Diamondbacks have a 14-20 NRFI record.

Last Time They Met

The Diamondbacks recorded a lopsided 9-0 victory against the Pirates at Chase Field yesterday. Ketel Marte went yard en route to that victory, hitting a home run to go with 2 RBIs.