MLB Prop Bets: San Diego Padres vs Cincinnati Reds (September 10, 2025)
The Cincinnati Reds (73-72) face the San Diego Padres (79-66) at Petco Park on Wednesday at 8:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Andrew Abbott is the probable pitcher for the Reds, while Nick Pivetta is the probable pitcher for the Padres. The Padres are favored to win at -169, while the Reds are at +138. The total runs line is set at 7.5, with OVER at -108 and UNDER at -113.
- The Reds (-157) have a 74-71 Run Line record this season, while the Padres (+128) hold a record of 79-66.
- The Reds have a 54-83-8 O/U record this season (meaning 54 games have gone over the total runs line, 83 have gone under and eight have resulted in a push). The Padres have a 61-79-5 O/U record.
Scoring Insights
- The Reds are averaging 4.5 runs per game this season (13th in the league). Comparatively, the Padres are averaging only 4.2 (23rd).
- In the field, the Reds are allowing 4.3 runs per game this season (14th in the league), while the Padres are allowing an average of 3.9 runs (2nd).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Reds are at .246 (ranking 16th in the Major leagues), while the Padres are batting .252 (8th).
Home Runs
- In terms of total home runs this season, the Padres have hit 127 (29th in the Major Leagues). Meanwhile, the Reds have managed 146 (23rd).
Runs Batted In
- Finally, looking at their runs batted in, the Reds have recorded 618 RBIs to rank 13th in the MLB this season. Comparatively, the Padres have recorded 579 RBIs to rank 25th.
Pitching Insights:
Earned Run Average
- The Padres have an earned run average of 3.66 this season (3rd in the Majors), while The Reds have an ERA of 3.93 (14th).
Strikeouts
- Turning our attention to total strikeouts, the Reds have recorded 1232 this season, ranking 12th in the MLB. Meanwhile, the Padres rank 8th for total strikeouts, recording 1254.
Opponent Batting Average
- Opponents are batting an average of .226 against the Padres this season (1st in the Major Leagues). Comparatively, the Reds' opponents are at .236 (7th).
First Innings Moneyline
- Here are their first innings moneyline records in 2025.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 39-30-76 | 26-11-36 | 12-19-40 | 21-12-30 | 18-18-46 | 1-0-0 | 3-3-4 |
| Padres | 28-35-82 | 13-17-40 | 15-18-42 | 17-23-40 | 11-12-42 | 0-0-0 | 1-4-5 |
Lead After Three Innings
The Reds are +124 to lead after three innings, while the Padres are -159.
- Here are their records after the first three innings in 2025.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 50-53-42 | 32-23-18 | 18-29-24 | 21-18-24 | 29-35-18 | 0-1-0 | 6-3-1 |
| Padres | 50-55-40 | 26-24-20 | 24-31-20 | 29-32-19 | 21-23-21 | 0-0-0 | 2-7-1 |
NRFI/YRFI
The NRFI market is paying -125 and the YRFI is paying -106.
- The NRFI is 72-73 in Reds games this season. The Padres have a 79-66 NRFI record.
Last Time They Met
The Reds recorded an upset 4-2 victory over the Padres at Petco Park yesterday. Despite being on the wrong side of that result, Jackson Merrill did what he could, hitting a home run. That result snapped the Padres' three-game winning streak against the Reds at Petco Park.
