MLB Prop Bets: Boston Red Sox vs New York Yankees (April 22, 2026)
The New York Yankees (14-9) face the Boston Red Sox (9-14) at Fenway Park on Wednesday at 6:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Max Fried is the probable pitcher for the Yankees, while Ranger Suarez is the probable pitcher for the Red Sox. The Yankees are favored to win at -143, while the Red Sox are at +119. The total runs line is set at 8.0, with OVER at -104 and UNDER at -116.
- The Yankees (+119) have a 12-11 Run Line record this season, while the Red Sox (-143) hold a record of 7-16.
- The Yankees have a 9-12-2 O/U record this season (meaning nine games have gone over the total runs line, 12 have gone under and two have resulted in a push). The Red Sox have a 12-11-0 O/U record.
Scoring Insights
- The Yankees are averaging 5.0 runs per game this season (T8th in the league). Comparatively, the Red Sox are averaging only 3.9 (24th).
- In the field, the Yankees are allowing only 3.6 runs per game this season (4th in the league), while the Red Sox are allowing an average of 4.6 runs (19th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Yankees are at .222 (ranking 25th in the Major leagues), while the Red Sox are batting .229 (20th).
Home Runs
- In terms of total home runs this season, the Yankees are one of the best in the Major Leagues, hitting 33 to rank 3rd. Alternatively, the Red Sox are at the opposite end of the home run standings, hitting just 13 (T29th).
Runs Batted In
- Finally, looking at their runs batted in, the Yankees have recorded 107 RBIs to rank 11th in the MLB this season. Comparatively, the Red Sox have recorded 84 RBIs to rank T25th.
Pitching Insights:
Earned Run Average
- The Red Sox have an earned run average of 4.40 this season (22nd in the Majors), while The Yankees have an ERA of 3.25 (3rd).
Strikeouts
- Turning our attention to total strikeouts, the Yankees have recorded 205 this season, ranking T13th in the MLB. Meanwhile, the Red Sox rank 27th for total strikeouts, recording 179.
Opponent Batting Average
- Opponents are batting an average of .243 against the Red Sox this season (20th in the Major Leagues). Comparatively, the Yankees' opponents are at .225 (7th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Yankees | 8-4-11 | 6-3-4 | 2-1-7 | 7-4-10 | 1-0-1 | 0-0-0 | 3-3-4 |
| Red Sox | 2-8-13 | 1-1-9 | 1-7-4 | 1-6-13 | 1-2-0 | 0-0-0 | 1-4-5 |
Lead After Three Innings
The Yankees are -145 to lead after three innings, while the Red Sox are +114.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Yankees | 13-6-4 | 8-3-2 | 5-3-2 | 11-6-4 | 2-0-0 | 0-0-0 | 6-2-2 |
| Red Sox | 7-9-7 | 5-3-3 | 2-6-4 | 6-7-7 | 1-2-0 | 0-0-0 | 3-4-3 |
NRFI/YRFI
The NRFI market is paying -150 and the YRFI is paying +115.
- The NRFI is 10-13 in Yankees games this season. The Red Sox have a 12-11 NRFI record.
Last Time They Met
The Yankees recorded a 4-0 victory over the Red Sox at Fenway Park yesterday. Giancarlo Stanton was unstoppable in that matchup, hitting a home run, a double and recording 3 RBIs. The Yankees have now won three straight against the Red Sox.
