MLB Prop Bets: Chicago Cubs vs Philadelphia Phillies (April 22, 2026)
The Philadelphia Phillies (8-15) face the Chicago Cubs (14-9) at Wrigley Field on Wednesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Kyle Backhus is the probable pitcher for the Phillies, while Matthew Boyd is the probable pitcher for the Cubs. The Cubs are favored to win at -175, while the Phillies are at +144. The total runs line is set at 8.5, with OVER at -108 and UNDER at -112.
- The Phillies (-143) have a 4-19 Run Line record this season, while the Cubs (+119) hold a record of 11-12.
- The Phillies have an 11-11-1 O/U record this season (meaning 11 games have gone over the total runs line, 11 have gone under and one has resulted in a push). The Cubs have a 13-9-1 O/U record.
Scoring Insights
- The Phillies are averaging 3.5 runs per game this season (27th in the league). Comparatively, the Cubs are averaging +1.9 more at 5.4 runs (5th).
- In the field, the Phillies are allowing a whopping 5.4 runs per game this season (27th in the league), while the Cubs are allowing an average of 3.8 runs (6th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cubs are at an impressive .255 (ranking 4th in the Major leagues), while the Phillies are batting an underwhelming .218 (28th).
Home Runs
- In terms of total home runs this season, the Cubs have hit 27 (T7th in the Major Leagues). Meanwhile, the Phillies have managed 24 (T15th).
Runs Batted In
- Finally, looking at their runs batted in, the Phillies have recorded 79 RBIs to rank 27th in the MLB this season. Comparatively, the Cubs have recorded 110 RBIs to rank 9th.
Pitching Insights:
Earned Run Average
- The Cubs have an earned run average of 3.45 this season (7th in the Majors), while The Phillies have an ERA of 4.99 (28th).
Strikeouts
- Turning our attention to total strikeouts, the Phillies have recorded 225 this season, ranking 4th in the MLB. Meanwhile, the Cubs rank T24th for total strikeouts, recording 185.
Opponent Batting Average
- Opponents are batting an average of only .222 against the Cubs this season (5th in the Major Leagues). Alternatively, the Phillies' opponents are at .278 (30th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 8-6-9 | 6-4-5 | 2-2-4 | 7-5-7 | 1-1-2 | 0-0-0 | 3-2-5 |
| Cubs | 3-4-16 | 2-2-10 | 1-2-6 | 2-2-13 | 1-2-3 | 0-0-0 | 1-3-6 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Phillies | 8-11-4 | 7-7-1 | 1-4-3 | 7-9-3 | 1-2-1 | 0-0-0 | 4-5-1 |
| Cubs | 10-6-7 | 6-3-5 | 4-3-2 | 8-3-6 | 2-3-1 | 0-0-0 | 3-4-3 |
NRFI/YRFI
The NRFI market is paying -135 and the YRFI is paying +105.
- The NRFI is 9-14 in Phillies games this season. The Cubs have a 16-7 NRFI record.
Last Time They Met
The Cubs recorded a 7-4 victory over the Phillies at Wrigley Field yesterday. Seiya Suzuki was unstoppable in that matchup, hitting a home run, a single and recording 2 RBIs. The Cubs have now won four straight against the Phillies.
