MLB Prop Bets: Tampa Bay Rays vs Cincinnati Reds (April 22, 2026)
The Cincinnati Reds (16-8) face the Tampa Bay Rays (12-11) at Tropicana Field on Wednesday at 1:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Brandon Williamson is the probable pitcher for the Reds, while Nick Martinez is the probable pitcher for the Rays. The Rays are favored to win at -143, while the Reds are at +119. The total runs line is set at 8.0, with OVER at -115 and UNDER at -105.
- The Reds (-181) have a 15-9 Run Line record this season, while the Rays (+149) hold a record of 12-11.
- The Reds have a 13-11-0 O/U record this season (meaning 13 games have gone over the total runs line and 11 have gone under). The Rays have a 15-6-2 O/U record.
Scoring Insights
- The Reds are averaging 4.0 runs per game this season (T22nd in the league). Comparatively, the Rays are averaging +0.8 more at 4.8 runs (11th).
- In the field, the Reds are allowing 3.9 runs per game this season (8th in the league), while the Rays are allowing an average of 5.5 runs (28th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Rays are at an impressive .255 (ranking 5th in the Major leagues), while the Reds are batting an underwhelming .207 (30th).
Home Runs
- In terms of total home runs this season, the Rays have hit 19 (T21st in the Major Leagues). Meanwhile, the Reds have managed 27 (T7th).
Runs Batted In
- Finally, looking at their runs batted in, the Reds have recorded 87 RBIs to rank 24th in the MLB this season. Comparatively, the Rays have recorded 104 RBIs to rank 12th.
Pitching Insights:
Earned Run Average
- The Rays have an earned run average of 4.86 this season (27th in the Majors), while The Reds have an ERA of 3.47 (9th).
Strikeouts
- Turning our attention to total strikeouts, the Reds have recorded 187 this season, ranking T22nd in the MLB. Meanwhile, the Rays rank T22nd for total strikeouts, recording 187.
Opponent Batting Average
- Opponents are batting an average of .232 against the Rays this season (12th in the Major Leagues). Comparatively, the Reds' opponents are at .227 (9th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 6-5-13 | 3-2-7 | 3-3-6 | 2-0-4 | 4-5-9 | 0-0-0 | 4-3-3 |
| Rays | 5-6-12 | 1-3-4 | 4-3-8 | 2-4-8 | 3-2-4 | 0-0-0 | 2-4-4 |
Lead After Three Innings
The Reds are +114 to lead after three innings, while the Rays are -145.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 7-8-9 | 4-4-4 | 3-4-5 | 3-1-2 | 4-7-7 | 0-0-0 | 5-3-2 |
| Rays | 10-10-3 | 3-3-2 | 7-7-1 | 6-7-1 | 4-3-2 | 0-0-0 | 3-6-1 |
NRFI/YRFI
The NRFI market is paying -125 and the YRFI is paying -105.
- The NRFI is 12-12 in Reds games this season. The Rays have an 11-12 NRFI record.
Last Time They Met
The Reds recorded a 12-6 victory over the Rays at Tropicana Field yesterday. Elly De La Cruz was crushing the ball in that matchup, hitting 2 home runs and recording 5 RBIs. The Reds have now won five straight against the Rays.
