MLB Prop Bets: Boston Red Sox vs New York Yankees (April 21, 2026)
The New York Yankees (13-9) face the Boston Red Sox (9-13) at Fenway Park on Tuesday at 6:45pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Luis Gil is the probable pitcher for the Yankees, while Connelly Early is the probable pitcher for the Red Sox. The Red Sox opened as favorites but this has since changed, with the Yankees coming into -115 and Red Sox drifting to -105. The total runs line is set at 8.5, with OVER at -105 and UNDER at -115.
- The Yankees (+139) have an 11-11 Run Line record this season, while the Red Sox (-168) hold a record of 7-15.
- The Yankees have a 9-11-2 O/U record this season (meaning nine games have gone over the total runs line, 11 have gone under and two have resulted in a push). The Red Sox have a 12-10-0 O/U record.
Scoring Insights
- The Yankees are averaging 5.0 runs per game this season (9th in the league). Comparatively, the Red Sox are averaging only 4.0 (20th).
- In the field, the Yankees are allowing only 3.7 runs per game this season (T5th in the league), while the Red Sox are allowing an average of 4.6 runs (T19th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Yankees are at .218 (ranking 27th in the Major leagues), while the Red Sox are batting .233 (16th).
Home Runs
- In terms of total home runs this season, the Yankees are one of the best in the Major Leagues, hitting 32 to rank 3rd. Alternatively, the Red Sox are at the opposite end of the home run standings, hitting just 13 (T29th).
Runs Batted In
- Finally, looking at their runs batted in, the Yankees have recorded 103 RBIs to rank T9th in the MLB this season. Comparatively, the Red Sox have recorded 84 RBIs to rank 24th.
Pitching Insights:
Earned Run Average
- The Red Sox have an earned run average of 4.42 this season (21st in the Majors), while The Yankees have an ERA of 3.40 (6th).
Strikeouts
- Turning our attention to total strikeouts, the Yankees have recorded 201 this season, ranking T10th in the MLB. Meanwhile, the Red Sox rank T26th for total strikeouts, recording 170.
Opponent Batting Average
- Opponents are batting an average of .241 against the Red Sox this season (17th in the Major Leagues). Comparatively, the Yankees' opponents are at .229 (10th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Yankees | 8-4-10 | 6-3-4 | 2-1-6 | 7-4-10 | 1-0-0 | 0-0-0 | 3-3-4 |
| Red Sox | 2-8-12 | 1-1-8 | 1-7-4 | 1-6-12 | 1-2-0 | 0-0-0 | 1-4-5 |
Lead After Three Innings
The Yankees are -115 to lead after three innings, while the Red Sox are -115.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Yankees | 12-6-4 | 8-3-2 | 4-3-2 | 11-6-4 | 1-0-0 | 0-0-0 | 5-3-2 |
| Red Sox | 7-8-7 | 5-2-3 | 2-6-4 | 6-6-7 | 1-2-0 | 0-0-0 | 3-4-3 |
NRFI/YRFI
The NRFI market is paying -115 and the YRFI is paying -110.
- The NRFI is 9-13 in Yankees games this season. The Red Sox have an 11-11 NRFI record.
Last Time They Met
The Yankees recorded a 4-0 victory over the Red Sox at Yankee Stadium when these teams last met in the 2025 Wild Card Series. Giancarlo Stanton led the way to that victory, hitting a home run.
