MLB Prop Bets: Tampa Bay Rays vs Cincinnati Reds (April 21, 2026)
The Cincinnati Reds (15-8) face the Tampa Bay Rays (12-10) at Tropicana Field on Tuesday at 6:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Chase Burns is the probable pitcher for the Reds, while Steven Matz is the probable pitcher for the Rays. The Reds opened as favorites but this matchup has since become a pick'em, with both the Reds and Rays at -110 to win. The total runs line is set at 7.5, with OVER at +100 and UNDER at -120.
- The Reds (+149) have a 14-9 Run Line record this season, while the Rays (-181) hold a record of 12-10.
- The Reds have a 12-11-0 O/U record this season (meaning 12 games have gone over the total runs line and 11 have gone under). The Rays have a 14-6-2 O/U record.
Scoring Insights
- The Reds are averaging 3.7 runs per game this season (26th in the league). Comparatively, the Rays are averaging +1.1 more at 4.7 runs (12th).
- In the field, the Reds are allowing 3.8 runs per game this season (9th in the league), while the Rays are allowing an average of 5.2 runs (26th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Rays are at an impressive .256 (ranking 4th in the Major leagues), while the Reds are batting an underwhelming .204 (30th).
Home Runs
- In terms of total home runs this season, the Rays have hit 18 (T22nd in the Major Leagues). Meanwhile, the Reds have managed 22 (T17th).
Runs Batted In
- Finally, looking at their runs batted in, the Reds have recorded 75 RBIs to rank T25th in the MLB this season. Comparatively, the Rays have recorded 98 RBIs to rank 13th.
Pitching Insights:
Earned Run Average
- The Rays have an earned run average of 4.54 this season (23rd in the Majors), while The Reds have an ERA of 3.36 (4th).
Strikeouts
- Turning our attention to total strikeouts, the Reds have recorded 175 this season, ranking 25th in the MLB. Meanwhile, the Rays rank 24th for total strikeouts, recording 176.
Opponent Batting Average
- Opponents are batting an average of .230 against the Rays this season (11th in the Major Leagues). Comparatively, the Reds' opponents are at .227 (8th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 5-5-13 | 3-2-7 | 2-3-6 | 1-0-4 | 4-5-9 | 0-0-0 | 3-3-4 |
| Rays | 5-5-12 | 1-2-4 | 4-3-8 | 2-4-8 | 3-1-4 | 0-0-0 | 2-3-5 |
Lead After Three Innings
The Reds are -125 to lead after three innings, while the Rays are -105.
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Reds | 6-8-9 | 4-4-4 | 2-4-5 | 2-1-2 | 4-7-7 | 0-0-0 | 4-4-2 |
| Rays | 10-9-3 | 3-2-2 | 7-7-1 | 6-7-1 | 4-2-2 | 0-0-0 | 4-5-1 |
NRFI/YRFI
The NRFI market is paying -145 and the YRFI is paying +110.
- The NRFI is 12-11 in Reds games this season. The Rays have an 11-11 NRFI record.
Last Time They Met
The Reds recorded a 6-1 victory over the Rays at Tropicana Field yesterday. Sal Stewart was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs. The Reds have now won four straight against the Rays.
