

MLB Prop Bets: Colorado Rockies vs San Diego Padres (April 21, 2026)
The San Diego Padres (15-7) face the Colorado Rockies (9-14) at Coors Field on Tuesday at 8:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Randy Vasquez is the probable pitcher for the Padres, while the Rockies' probable pitcher remains unclear. The Padres are favored to win at -143, while the Rockies are at +119. The total runs line is set at 11.0, with OVER at -110 and UNDER at -110.
- The Padres (+104) have a 13-9 Run Line record this season, while the Rockies (-126) hold a record of 14-9.
- The Padres have a 9-12-1 O/U record this season (meaning nine games have gone over the total runs line, 12 have gone under and one has resulted in a push). The Rockies have a 9-14-0 O/U record.
Scoring Insights
- The Padres are averaging 4.4 runs per game this season (15th in the league). Comparatively, the Rockies are averaging 4.0 (T22nd).
- In the field, the Padres are allowing only 3.6 runs per game this season (3rd in the league), while the Rockies are allowing an average of 4.8 runs (22nd).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Padres are at .232 (ranking 17th in the Major leagues), while the Rockies are batting .244 (13th).
Home Runs
- In terms of total home runs this season, the Rockies have hit 23 (T14th in the Major Leagues). Meanwhile, the Padres have managed 17 (T25th).
Runs Batted In
- Finally, looking at their runs batted in, the Padres have recorded 91 RBIs to rank T19th in the MLB this season. Comparatively, the Rockies have recorded 89 RBIs to rank 21st.
Pitching Insights:
Earned Run Average
- The Rockies have an earned run average of 4.40 this season (20th in the Majors), while The Padres have an ERA of 3.36 (5th).
Strikeouts
- Turning our attention to total strikeouts, the Padres have recorded an impressive 212 this season, ranking 6th in the MLB. Contrastingly, the Rockies rank T26th for total strikeouts, recording only 170.
Opponent Batting Average
- Opponents are batting an average of .269 against the Rockies this season (28th in the Major Leagues). Comparatively, the Padres' opponents are at .231 (12th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Padres | 2-3-17 | 2-3-8 | 0-0-9 | 2-1-9 | 0-2-8 | 0-0-0 | 1-1-8 |
| Rockies | 6-8-9 | 3-5-2 | 3-3-7 | 0-0-0 | 6-8-9 | 0-0-0 | 3-5-2 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Padres | 6-8-8 | 5-5-3 | 1-3-5 | 3-3-6 | 3-5-2 | 0-0-0 | 3-3-4 |
| Rockies | 4-12-7 | 2-6-2 | 2-6-5 | 0-0-0 | 4-12-7 | 0-0-0 | 1-8-1 |
NRFI/YRFI
The NRFI market is paying +110 and the YRFI is paying -145.
- The NRFI is 17-5 in Padres games this season. The Rockies have a 9-14 NRFI record.
Last Time They Met
The Padres recorded a 7-2 victory over the Rockies at Petco Park when these teams last met on April 12. Ty France was unstoppable in that matchup, hitting a home run, a double and recording an RBI. The Padres have now won six straight against the Rockies.



























