MLB Prop Bets: Chicago White Sox vs Chicago Cubs (May 16, 2026)
The Chicago Cubs (29-16) face the Chicago White Sox (22-22) at Rate Field on Saturday at 7:10pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Jameson Taillon is the probable pitcher for the Cubs, while Davis Martin is the probable pitcher for the White Sox. This contest is a pick'em, with both the Cubs and White Sox at -110 to win. The total runs line is set at 8.5, with OVER at -107 and UNDER at -113.
- The Cubs (+149) have a 22-23 Run Line record this season, while the White Sox (-181) hold a record of 23-21.
- The Cubs have a 24-19-2 O/U record this season (meaning 24 games have gone over the total runs line, 19 have gone under and two have resulted in a push). The White Sox have a 25-19-0 O/U record.
Scoring Insights
- The Cubs are averaging 5.1 runs per game this season (3rd in the league). Comparatively, the White Sox are averaging only 4.4 (13th).
- In the field, the Cubs are allowing 4.0 runs per game this season (9th in the league), while the White Sox are allowing an average of 4.7 runs (21st).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cubs are at .247 (ranking 8th in the Major leagues), while the White Sox are batting .234 (22nd).
Home Runs
- In terms of total home runs this season, the White Sox have hit 59 (T3rd in the Major Leagues). Meanwhile, the Cubs have managed 53 (T8th).
Runs Batted In
- Finally, looking at their runs batted in, the Cubs have recorded 212 RBIs to rank 5th in the MLB this season. Comparatively, the White Sox have recorded 184 RBIs to rank T15th.
Pitching Insights:
Earned Run Average
- The White Sox have an earned run average of 4.35 this season (19th in the Majors), while The Cubs have an ERA of 3.80 (10th).
Strikeouts
- Turning our attention to total strikeouts, the Cubs have recorded 367 this season, ranking 19th in the MLB. Meanwhile, the White Sox rank 21st for total strikeouts, recording 351.
Opponent Batting Average
- Opponents are batting an average of .243 against the White Sox this season (19th in the Major Leagues). Comparatively, the Cubs' opponents are at .229 (9th).
First Innings Moneyline
- Here are their first innings moneyline records in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cubs | 8-7-30 | 5-3-15 | 3-4-15 | 7-3-20 | 1-4-10 | 0-0-0 | 3-1-6 |
| White Sox | 13-9-22 | 6-5-11 | 7-4-11 | 0-1-5 | 13-8-17 | 0-0-0 | 4-3-3 |
Lead After Three Innings
- Here are their records after the first three innings in 2026.
| Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
|---|---|---|---|---|---|---|---|
| Cubs | 21-12-12 | 13-5-5 | 8-7-7 | 16-6-8 | 5-6-4 | 0-0-0 | 3-3-4 |
| White Sox | 20-13-11 | 10-6-6 | 10-7-5 | 0-3-3 | 20-10-8 | 0-0-0 | 4-3-3 |
NRFI/YRFI
- The NRFI is 30-15 in Cubs games this season. The White Sox have a 21-23 NRFI record.
Last Time They Met
The Cubs recorded a 10-5 victory over the White Sox at Rate Field yesterday. Miguel Vargas was unstoppable in that matchup, hitting a home run, a double and recording an RBI. The Cubs have now won three straight against the White Sox.
