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MLB Prop Bets: Washington Nationals vs Baltimore Orioles (May 16, 2026)

The Baltimore Orioles (20-25) face the Washington Nationals (22-23) at Nationals Park on Saturday at 4:05pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Chris Bassitt is the probable pitcher for the Orioles, while Cade Cavalli is the probable pitcher for the Nationals. This contest is a pick'em, with both the Orioles and Nationals at -110 to win. The total runs line is set at 10.0, with OVER at -104 and UNDER at -116.

  • The Orioles (+139) have a 19-26 Run Line record this season, while the Nationals (-168) hold a record of 27-18.
  • The Orioles have a 24-20-1 O/U record this season (meaning 24 games have gone over the total runs line, 20 have gone under and one has resulted in a push). The Nationals have a 28-16-1 O/U record.

Scoring Insights

  • The Orioles are averaging 4.3 runs per game this season (14th in the league). Comparatively, the Nationals are averaging +1.0 more at 5.3 runs (2nd).
  • In the field, the Orioles are allowing a whopping 5.2 runs per game this season (28th in the league), while the Nationals are allowing an average of 5.7 runs (30th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Orioles are at .230 (ranking 26th in the Major leagues), while the Nationals are batting .241 (13th).

Home Runs

  • In terms of total home runs this season, the Nationals have hit 53 (T7th in the Major Leagues). Meanwhile, the Orioles have managed 44 (T16th).

Runs Batted In

  • Finally, looking at their runs batted in, the Orioles have recorded 192 RBIs to rank 11th in the MLB this season. Comparatively, the Nationals have recorded 224 RBIs to rank 2nd.

Pitching Insights:

Earned Run Average

  • The Nationals have an earned run average of 4.95 this season (29th in the Majors), while The Orioles have an ERA of 4.58 (26th).

Strikeouts

  • Turning our attention to total strikeouts, the Orioles have recorded 370 this season, ranking T16th in the MLB. Meanwhile, the Nationals rank 22nd for total strikeouts, recording 345.

Opponent Batting Average

  • Opponents are batting an average of .255 against the Nationals this season (26th in the Major Leagues). Comparatively, the Orioles' opponents are at .259 (27th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Orioles 5-10-30 3-4-17 2-6-13 3-3-20 2-7-10 0-0-0 1-3-6
    Nationals 15-9-21 8-4-8 7-5-13 0-1-1 15-8-20 0-0-0 3-1-6

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Orioles 11-21-13 8-10-6 3-11-7 6-10-10 5-11-3 0-0-0 2-4-4
    Nationals 14-20-11 6-9-5 8-11-6 0-0-2 14-20-9 0-0-0 3-5-2

NRFI/YRFI

  • The NRFI is 28-17 in Orioles games this season. The Nationals have a 21-24 NRFI record.

Last Time They Met

The Nationals recorded a 3-2 victory over the Orioles at Nationals Park yesterday. Daylen Lile was unstoppable in that matchup, hitting a home run, a double and recording 2 RBIs. The Nationals have now won four straight against the Orioles.