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MLB Prop Bets: Seattle Mariners vs San Diego Padres (May 16, 2026)

The San Diego Padres (26-18) face the Seattle Mariners (22-24) at T-Mobile Park on Saturday at 7:15pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Walker Buehler is the probable pitcher for the Padres, while Logan Gilbert is the probable pitcher for the Mariners. The Mariners are favored to win at -168, while the Padres are at +139. The total runs line is set at 7.0, with OVER at -120 and UNDER at +100.

  • The Padres (-163) have a 21-23 Run Line record this season, while the Mariners (+135) hold a record of 19-27.
  • The Padres have an 18-25-1 O/U record this season (meaning 18 games have gone over the total runs line, 25 have gone under and one has resulted in a push). The Mariners have a 20-25-1 O/U record.

Scoring Insights

  • The Padres are averaging 4.1 runs per game this season (25th in the league). Comparatively, the Mariners are averaging 4.2 (21st).
  • In the field, the Padres are allowing 4.1 runs per game this season (10th in the league), while the Mariners are allowing an average of 3.8 runs (6th).

Let's take a look at how these teams perform in some other key statistical areas.

Batting Insights:

Batting Average

  • Looking at their batting averages this season, the Padres are at .223 (ranking 30th in the Major leagues), while the Mariners are batting .232 (23rd).

Home Runs

  • In terms of total home runs this season, the Mariners have hit 53 (T8th in the Major Leagues). Meanwhile, the Padres have managed 41 (20th).

Runs Batted In

  • Finally, looking at their runs batted in, the Padres have recorded 173 RBIs to rank 26th in the MLB this season. Comparatively, the Mariners have recorded 186 RBIs to rank 13th.

Pitching Insights:

Earned Run Average

  • The Mariners have an earned run average of 3.58 this season (6th in the Majors), while The Padres have an ERA of 4.04 (15th).

Strikeouts

  • Turning our attention to total strikeouts, the Padres have recorded 386 this season, ranking 12th in the MLB. Meanwhile, the Mariners rank 11th for total strikeouts, recording 391.

Opponent Batting Average

  • Opponents are batting an average of .253 against the Mariners this season (24th in the Major Leagues). Comparatively, the Padres' opponents are at .238 (12th).

First Innings Moneyline

  • Here are their first innings moneyline records in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 5-7-32 4-3-16 1-4-14 5-3-18 0-4-14 0-0-2 1-2-7
    Mariners 12-12-22 8-8-8 4-4-14 12-11-18 0-1-4 0-0-0 3-2-5

Lead After Three Innings

  • Here are their records after the first three innings in 2026.
    Total Home Road Favorite Underdog Neutral Last 10
    Padres 8-20-16 6-10-7 1-9-9 5-10-11 3-10-5 1-1-0 1-3-6
    Mariners 19-15-12 11-8-5 8-7-7 16-14-11 3-1-1 0-0-0 6-1-3

NRFI/YRFI

The NRFI market is paying -140 and the YRFI is paying +110.

  • The NRFI is 32-12 in Padres games this season. The Mariners have a 19-27 NRFI record.

Last Time They Met

The Padres recorded a 2-0 victory over the Mariners at T-Mobile Park yesterday. Gavin Sheets led the way to that victory, hitting a home run. The Padres have now won four straight against the Mariners.